Experimentally-Induced Paw Oedemas in Mice

"The present monograph on inflammation models for experimental induction of paw oedema in the mouse has at least two major merits. Firstly, it provides a comprehensive compendium of the different aspects linked to the application of this experimental model, covering mediator generation, rapid vascular responses with oedema associated to leucocyte infiltration, sterile stimulation as well as bacterial and other pathogen-derived product induced oedema. Secondly, it represents a must-have reference book for anybody interested in developing new anti-inflammatory therapeutics. It is definitively a must for colleagues in the pharmaceutical industry interested in drug discovery." (Prof. Mauro Perretti)